Basic, Translational, and Clinical Research

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Patient-Specific Drug Screening Using a Human Induced Pluripotent Stem Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Type 2
Leonid Maizels, Irit Huber, Gil Arbel, Anke J. Tijsen, Amira Gepstein, Asaad Khoury and Lior Gepstein

Circulation: Arrhythmia and Electrophysiology. 2017;10:e004725, originally published June 19, 2017
https://doi.org/10.1161/CIRCEP.116.004725

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Distinctive Left Ventricular Activations Associated With ECG Pattern in Heart Failure Patients
Nicolas Derval, Josselin Duchateau, Saagar Mahida, Romain Eschalier, Frederic Sacher, Joost Lumens, Hubert Cochet, Arnaud Denis, Xavier Pillois, Seigo Yamashita, Yuki Komatsu, Sylvain Ploux, Sana Amraoui, Adlane Zemmoura, Philippe Ritter, Mélèze Hocini, Michel Haissaguerre, Pierre Jaïs and Pierre Bordachar

Circulation: Arrhythmia and Electrophysiology. 2017;10:e005073, originally published June 19, 2017
https://doi.org/10.1161/CIRCEP.117.005073

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Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the I_Ks Amplitude in Check Until When Larger I_Ks Is Needed
Min Jiang, Yuhong Wang and Gea-Ny Tseng

Circulation: Arrhythmia and Electrophysiology. 2017;10:e005084, originally published June 13, 2017
https://doi.org/10.1161/CIRCEP.117.005084

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Induced Pluripotent Stem Cell–Based Treatment of Acquired Heart BlockThe Battle for Tomorrow Has Begun!
Wenbin Liang, Aizhu Lu and Darryl R. Davis

Circulation: Arrhythmia and Electrophysiology. 2017;10:e005331, originally published May 12, 2017
https://doi.org/10.1161/CIRCEP.117.005331

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Induced Pluripotent Stem Cell–Derived Cardiomyocytes Provide In Vivo Biological Pacemaker Function
Samuel Chauveau, Evgeny P. Anyukhovsky, Meital Ben-Ari, Shulamit Naor, Ya-Ping Jiang, Peter Danilo, Tania Rahim, Stephanie Burke, Xiaoliang Qiu, Irina A. Potapova, Sergey V. Doronin, Peter R. Brink, Ofer Binah, Ira S. Cohen and Michael R. Rosen

Circulation: Arrhythmia and Electrophysiology. 2017;10:e004508, originally published May 12, 2017
https://doi.org/10.1161/CIRCEP.116.004508

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TGF-β₁ (Transforming Growth Factor-β₁) Plays a Pivotal Role in Cardiac Myofibroblast Arrhythmogenicity
Nicolò Salvarani, Ange Maguy, Stefano A. De Simone, Michele Miragoli, Florian Jousset and Stephan Rohr

Circulation: Arrhythmia and Electrophysiology. 2017;10:e004567, originally published May 12, 2017
https://doi.org/10.1161/CIRCEP.116.004567

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Spatial Resolution Requirements for Accurate Identification of Drivers of Atrial Fibrillation
Caroline H. Roney, Chris D. Cantwell, Jason D. Bayer, Norman A. Qureshi, Phang Boon Lim, Jennifer H. Tweedy, Prapa Kanagaratnam, Nicholas S. Peters, Edward J. Vigmond and Fu Siong Ng

Circulation: Arrhythmia and Electrophysiology. 2017;10:e004899, originally published May 12, 2017
https://doi.org/10.1161/CIRCEP.116.004899

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Mitral-Aortic Flow Reversal in Cardiac Resynchronization TherapyCoupling With Ejection and Impact of Variations in Atrioventricular Delay
Daniel Rodríguez Muñoz, José Luis Moya Mur, Javier Moreno, Covadonga Fernández-Golfín, Eduardo Franco, Bostjan Berlot, Juan Manuel Monteagudo, Roberto Matía Francés, Antonio Hernández Madrid and José Luis Zamorano

Circulation: Arrhythmia and Electrophysiology. 2017;10:e004927, originally published May 12, 2017
https://doi.org/10.1161/CIRCEP.116.004927

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Is TGF-β₁ (Transforming Growth Factor-β₁) an Enabler of Myofibroblast–Cardiomyocyte Cross Talk?
Kuljeet Kaur and José Jalife

Circulation: Arrhythmia and Electrophysiology. 2017;10:e005289, originally published May 12, 2017
https://doi.org/10.1161/CIRCEP.117.005289

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Drug-Induced Arrhythmias, Precision Medicine, and Small Data
Glenn I. Fishman

Circulation: Arrhythmia and Electrophysiology. 2017;10:e005208, originally published April 13, 2017
https://doi.org/10.1161/CIRCEP.117.005208

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