Response by Andrews et al to Letter Regarding Article, “Electrical and Structural Substrate of Arrhythmogenic Right Ventricular Cardiomyopathy Determined Using Noninvasive Electrocardiographic Imaging and Late Gadolinium Magnetic Resonance Imaging”
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We thank Dr Di Marco et al1 for their letter. We agree that contrast-enhanced multidetector computed tomography is excellent for noninvasively defining myocardial structure for electroanatomical map integration to determine, for example, the impact of epicardial fat.2
Myocardial tissue characterization by imaging, computed tomography (CT) and magnetic resonance imaging (MRI), provides insights into underlying activated disease pathways for focal fat and focal fibrosis in arrhythmogenic right ventricular cardiomyopathy (ARVC). How do they compare and how can they synergize?
Contraindications to MRI include presence of implanted devices and it has lower resolution than CT, but new approaches are emerging. Third-generation late gadolinium enhancement techniques with motion correction are superior while dark blood techniques3 visualize …