Letter by Morris et al Regarding Article, “Low Heart Rates Predict Incident Atrial Fibrillation in Healthy Middle-Aged Men” by Grundvold et al
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To the Editor:
We read with great interest the article by Grundvold et al1 describing low heart rate on exercise as a predictor of atrial fibrillation (AF) in healthy middle-aged men. The article makes an important contribution to the emerging body of evidence that exercise can lead to cardiovascular remodeling, increasing the risk of AF in later life. Although the authors concede that conclusions regarding the pathophysiological mechanisms underlying these observations are difficult, they argue that a predominance of parasympathetic tone may account for both low heart rate and …